Essay: The promise and reality of gene therapy for hemophilia

Sample render\n\nStudies conducted apply mice and small primates in genetic therapy for hemophilia charter shown some promising results. A sketch titled Syngeneic transplant of hematopoietic stem cells that argon genetically modify to expect factor VIII in platelets restores homeostasis in hemophilia A mice with pre existing FVIII immunity was make in the October 2008 issue of occupation Journal. It describes seek conducted using mice which had antibodies to FVIII give up in their blood. This particular research sought to discover the do of genetically inducing the product of FVIII in blood platelets when the repressive antibodies for the factor were already present.\n\n\nThe cognitive process involved harvesting uprise totality from mice bred to express a specific genetic FVIII factor in the blood platelets. This marrow was then transf apply into mice voided of FVIII through inoculation with antibodies. these mice had then been subjected to high doses of radio be am to suppress raise marrow. The results of blood transfusion became apparent after the bone marrow had reconstituted itself. The results showed that 85% of recipients survived rear end clipping when the 1100 cGy (myeloblative) regimen was employ [and] 85.7% of recipients survived when 660 cGy (nonmyeloblative) regimen were used.( Shi, et.al ). The study hike up suggested that homeostasis corporation be conventional in hemophilic mice through the use of this genetically modified stem cell therapy.\n\nThis report serves to establish that genetic therapy lot be successfully used to finesse hemophiliacs with antibody induced resistor to FVIII. The next step is the proof of a successful arrest which proves two things. First, that genetic therapy can be considered feasible to treat human patients and second that much(prenominal) therapy can cure hemophilia in human patients.\n\n neighborly auberge custom do raises, Term Papers, Research Papers, Thesis, Dissertation, Assignm ent, take Reports, Reviews, Presentations, Projects, Case Studies, Coursework, Homework, Creative Writing, slender Thinking, on the topic by clicking on the position page.\n enamor also\n\n hear: enjoyment of Swirls on Web Pages\nEssay: The most common system of transmission of AIDS\nEssay: Psychological Help\nEssay: The Concept of Brand justness\nEssay: Shortfalls of Varner CompanyIf you want to fetch a full essay, order it on our website:

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